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      Clinical trials

      Before a drug can be made available to the public it has to go through rigorous clinical trials, in people, to test whether it is safe and effective. To make sure these vital trials happen, we help companies engage with people with hearing loss and tinnitus (and help these people take part).

      Clinical trials establish whether a new treatment really does work better than a placebo (dummy) treatment – and if it has any dangerous side-effects.

      Clinical trials have different phases: initially, the drug is tested in small numbers of people to make sure that it is safe, before it is tested in hundreds and, sometimes, thousands of patients.

      This testing in large numbers is absolutely critical: reports of a good result in one or two patients do not necessarily mean that a therapy will be safe and effective for everyone.

      The process can take up to 10 years and cost millions of pounds. But, if a drug successfully completes all the phases of clinical-trial testing, health regulators and doctors can be confident that a new treatment is safe and has been proved to help the people who need it.

      How to take part in a clinical trial

      For up-to-date information on clinical trials in the UK – and why they are so important – please visit the UK Clinical Trials Gateway.

      If you're interested in taking part in an international clinical trial, taking place outside the UK, please use the World Health Organisation's International Clinical Trials Registry Platform on the NHS Choices website.

      Sign up for Soundbite

      If you’d like to find out about all the latest hearing research developments, sign up to receive our soundbite e-newsletter. It'll arrive in your email inbox every month, full of up-to-the-minute news and views on hearing and tinnitus research.

      Clinical trial news

      Cochlear implant (CI) users

      A clinical study to test Autifony Therapeutics' lead compound, AUT00063, in adult cochlear implant users has started in the UK. The clinical trial, which will be conducted at four sites (London, Birmingham, Cambridge and Manchester), is aimed at helping to improve the hearing of adult CI users, especially in discriminating speech in a noisy background.

      To find out more about the trial, go to the Autifony website.

      Ménière’s disease

      A clinical trial to test an investigational drug for Ménière’s disease is underway in the UK. Scientists want to find out if the drug reduces the number of vertigo episodes that Ménière’s disease patients endure.

      You can see all the details on the Ménière’s disease study website.

      TRIH Newsletter 

      Our bi-annual newsletter keeps you up to date with the latest opportunities in translational hearing research.

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      Even before we started formally funding research in 1999, our Technology Department was involved with research into hearing aids and cochlear implants, most notably as part of the team that...

      Everything you need to know about your hearing

      Are you looking for reliable information on all aspects of deafness, hearing loss and tinnitus? Read our range of factsheets and leaflets on a range of topics.