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      Professor Hrvoje Petkovic

      Hrvoje Petkovic is an Action on Hearing Loss-funded researcher at biotechnology company, Acies Bio, in Slovenia. We awarded him a Translational Research (TRIH) Grant to develop aminoglycoside antibiotics which are less toxic to the ear.

      Biography

      Hrvoje has over 20 years' experience in microbial biotechnology, focused on biosynthetic and metabolic engineering for process development and drug discovery.

      He has worked for and collaborated with large pharmaceutical companies and specialised biotechnology companies. He leads Research and Development at Acies Bio, a biotechnology SME (small or medium-sized enterprise) in Slovenia. He's also a visiting Professor of Biotechnology in the Biotechnical Faculty at the University of Ljubljana.

      Five minutes with Hrvoje Petkovic...

      What do you hope your research will achieve?

      Aminoglycoside antibiotics are highly effective antibiotics, whose use is severely curtailed by significant nephrotoxic (kidney-toxic) and ototoxic (ear-toxic) side effects.

      While kidney damage is often reversible, hearing damage in patients treated with these antibiotics is permanent. Nevertheless, in recent years, aminoglycosides have regained high clinical importance because of the emergence of multidrug-resistant (MDR) bacteria, as they are effective against these types of serious infections.

      So it's crucial that we find ways to reduce their ototoxicity, to avoid permanent hearing damage in those who receive these life-saving treatments.

      What does Action on Hearing Loss funding mean to you?

      We see Action on Hearing Loss as a visionary organisation, aiming to develop viable treatments to protect hearing and prevent tinnitus. With your very focused strategy to drive world-leading biomedical research into innovative solutions for hearing, through your Translational Research Initiative for Hearing (TRIH) grants, you support research organisations to make new discoveries.

      Find out more about Professor Hrvoje Petkovic's research project.

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